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KMID : 0370919940110010082
Yeungnam Univercity Journal of Medicine
1994 Volume.11 No. 1 p.82 ~ p.93
A Study on the Serologic Parameters in Patients with Anemia of Chronic Renal Failure-According to Erythropoietin Treatment
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Abstract
Clinical study was carried out on the 64 hemodialysis patients(HD) with chronic renal failure who had been treated from December 1992 to July 1993 in Yeungnam University Hospital.
@ES The following results were obitained.
In hematologic parameters, MCH was 28.8¡¾2.0pg, and MCV was 92.4¡¾4.7fl. Result revealed normochromic and normocytic anemia.
Mean values of serum ferritin were 657.4¡¾292.0ng/ml in men and 511.5¡¾370g in women. Mean values of serum iron were 145.5¡¾63.7§¶/dl. Mean values of transferrin saturation was 61.6¡¾28.4%. Serum frerritin, serum iron and transferrin saturation
were
higher in HD group than normal reference.
In erythropoeitin treatment group, Hb and Hct were significantly higher than non-erythropoietin treatment group. Amount of transfusion was significantly higher in non-erythropoietin treatment group than erythropoeitin treatment group(p<0.05).
Values of iron, transferrin saturation were significantly higher in abnormal liver function test(LFT0 hemodialysis group than normal LFT group(p<0.05).
Transfusion amounts revealed positive correlation with ferritin(r=0.4675), transferrin satruation (r=0.3823) and iron(r=0.3386) (p<0.05).
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